N-Boc-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid

N-Boc-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid - Names and Identifiers

Name	2-(Tert-Butoxycarbonyl)-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid
Synonyms	N-BOC-6-HYDROXYCARBONYL-1,2,3,4-TETRAHYDRO N-Boc-1,2,3,4-tetrahydroisoquinoline-6-carboxylic N-Boc-6-Hydroxycarbonyl-1,2,3,4-Tetrahydroisoquinoline N-Boc-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid 2-Boc-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid N-BOC-1,2,3,4-TETRAHYDROISOQUINOLINE-6-CARBOXYLIC ACID 3,4-DIHYDRO-1H-ISOQUINOLINE-2,6-DICARBOXYLIC ACID 2-TERT-BUTYL ESTER 3,4-Dihydro-1H-Isoquinoline-2,6-Dicarboxylic Acid 2-Tert-Butyl Ester 2-(Tert-Butoxycarbonyl)-1,2,3,4-Tetrahydroisoquinoline-6-Carbonic Acid 2-(TERT-BUTOXYCARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-6-CARBONIC ACID 2-(TERT-BUTOXYCARBONYL)-1,2,3,4-TETRAHYDROISOQUINOLINE-6-CARBOXYLIC ACID 2-(Tert-Butoxycarbonyl)-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid 2,6(1H)-Isoquinolinedicarboxylic acid, 3,4-dihydro-, 2-(1,1-dimethylethyl) ester
CAS	170097-67-3
InChI	InChI=1/C15H19NO4/c1-15(2,3)20-14(19)16-7-6-10-8-11(13(17)18)4-5-12(10)9-16/h4-5,8H,6-7,9H2,1-3H3,(H,17,18)

N-Boc-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid - Physico-chemical Properties

Molecular Formula	C15H19NO4
Molar Mass	277.32
Density	1?+-.0.06 g/cm3(Predicted)
Boling Point	429.3±45.0 °C(Predicted)
Flash Point	213.4°C
Vapor Presure	3.93E-08mmHg at 25°C
pKa	4.33±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.563

N-Boc-1,2,3,4-Tetrahydroisoquinoline-6-Carboxylic Acid - Introduction

2-(Tert-Butoxycarbonyl)-1,2,3, Acid is an organic compound that contains the Boc Group (t-butoxycarbonylaminomethyl) in its chemical structure. The following is an introduction to its nature, use, preparation and safety information:

Nature:
2-(Tert-Butoxycarbonyl)-1,2,3, Acid is a solid with a white to light yellow color. It is stable at room temperature, but will decompose under high temperature, strong acid and strong alkali conditions.

Use:
2-(Tert-Butoxycarbonyl)-1,2,3, Acid is often used as a protecting group (Boc protecting group) in organic chemical synthesis. It can be reacted with an amino compound to form a N-Boc protected amino compound. Such a protecting group can protect the amino group without interfering with other functional groups, allowing other parts of the molecule to undergo chemical reactions. It has a wide range of applications, including drug synthesis, multi-step organic synthesis and natural product synthesis.

Method:
2-(Tert-Butoxycarbonyl)-1,2,3, Acid is usually prepared by organic synthesis methods. One common method is to react N-Boc-aminocarbols with certain ring complexing reagents such as cyclopentadienyl diruthenium linkages (Cp2RuCl). The resulting intermediate is further reacted with 1,2,3,4-tetrahydroisoquinoline to give the desired product.

Safety Information:
2-(Tert-Butoxycarbonyl)-1,2,3, the use of Acid should pay attention to the following points:
1. It is a combustible material, to avoid contact with high temperature, flame and oxidant.
2. During use, be careful to avoid inhalation, contact with skin and eyes, and use personal protective equipment such as gloves, glasses and protective clothing when necessary.
3. During storage and handling, appropriate safety measures should be observed to avoid its leakage into the environment, and relevant laws and regulations should be observed.

Last Update：2024-04-09 02:00:43